HMM Summary Page: TIGR04216

Functionmajor cell surface glycoprotein
Gene Symbolcsg
Trusted Cutoff400.00
Domain Trusted Cutoff400.00
Noise Cutoff150.00
Domain Noise Cutoff150.00
Isology Typeequivalog
HMM Length784
AuthorHaft DH
Entry DateOct 12 2011 3:33PM
Last ModifiedJun 17 2014 4:02PM
CommentMembers of this family are the S-layer-forming halobacterial major cell surface glycoprotein. The highest scores below model cutoffs are fragmentary paralogs to actual members of the family. Modifications include at N-linked and O-linked glycosylation, a C-terminal diphytanylglyceryl modification, and probable cleavage of the PGF-CTERM tail.
ReferencesRN [1] RM PMID:10364251 RT Evidence for covalent attachment of diphytanylglyceryl phosphate to the cell-surface glycoprotein of Halobacterium halobium. RA Kikuchi A, Sagami H, Ogura K RL J Biol Chem. 1999 Jun 18;274(25):18011-6. RN [2] RM PMID:23651326 RT Haloferax volcanii archaeosortase is required for motility, mating, and C-terminal processing of the S-layer glycoprotein. RA Abdul Halim MF, Pfeiffer F, Zou J, Frisch A, Haft D, Wu S, Tolic N, Brewer H, Payne SH, Pasa-Tolic L, Pohlschroder M RL Mol Microbiol. 2013 Jun;88(6):1164-75. doi: 10.1111/mmi.12248. RN [3] RM PMID:24512091 RT Proteomic analysis of the secretome of haloarchaeon Natrinema sp. J7-2. RA Feng J, Wang J, Zhang Y, Du X, Xu Z, Wu Y, Tang W, Li M, Tang B, Tang XF RL J Proteome Res. 2014 Mar 7;13(3):1248-58. doi: 10.1021/pr400728x.