HMM Summary Page: TIGR03944

Function2,3-diaminopropionate biosynthesis protein SbnB
Trusted Cutoff326.90
Domain Trusted Cutoff326.90
Noise Cutoff254.65
Domain Noise Cutoff254.65
Isology Typeequivalog
HMM Length327
AuthorHaft DH
Entry DateFeb 22 2010 4:51PM
Last ModifiedFeb 14 2011 3:27PM
CommentMembers of this protein family are probable NAD-dependent dehydrogenases related to the alanine dehydrogenase of Archaeoglobus fulgidus (see TIGR02371, PDB structure 1OMO and PMID:15313611) and more distantly to ornithine cyclodeaminase. Members include the staphylobactin biosynthesis protein SbnB and tend to occur in contexts suggesting non-ribosomal peptide synthesis, always adjacent to (occasionally fused with) a pyridoxal phosphate-dependent enzyme, SbnA. The pair appears to provide 2,3-diaminopropionate for biosynthesis of siderophores or other secondary metabolites.
Genome PropertyGenProp0908: 2,3-diaminopropionic acid biosynthesis (HMM)