HMM Summary Page: TIGR03808

Functiontwin-arg-translocated uncharacterized repeat protein
Trusted Cutoff120.00
Domain Trusted Cutoff120.00
Noise Cutoff90.00
Domain Noise Cutoff90.00
Isology Typeequivalog
HMM Length455
AuthorHaft DH
Entry DateAug 14 2009 3:59PM
Last ModifiedFeb 14 2011 3:27PM
CommentMembers of this protein family have a Sec-independent twin-arginine tranlocation (TAT) signal sequence, which enables tranfer of proteins folded around prosthetic groups to cross the plasma membrane. These proteins have four copies of a repeat of about 23 amino acids that resembles the beta-helix repeat. Beta-helix refers to a structural motif in which successive beta strands wind around to stack parallel in a right-handed helix, as in AlgG and related enzymes of carbohydrate metabolism. The twin-arginine motif suggests that members of this protein family bind some unknown cofactor.
Genome PropertyGenProp0868: uncharacterized protein pair with twin-arg and repeat (HMM)