HMM Summary Page: TIGR03676

Functionpeptide chain release factor 1, archaeal and eukaryotic forms
Gene Symbolprf1
Trusted Cutoff234.70
Domain Trusted Cutoff234.70
Noise Cutoff146.15
Domain Noise Cutoff146.15
Isology Typeequivalog
HMM Length403
AuthorSelengut J, Anolik RT, Richardson DL, Haft DH
Entry DateOct 22 2008 2:00PM
Last ModifiedMar 25 2011 10:21AM
CommentDirects the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. This model identifies both archaeal (aRF1) and eukaryotic (eRF1) of the protein. Also known as translation termination factor 1.
ReferencesRN [1] RM PMID:10676813 RT The crystal structure of human eukaryotic release factor eRF1--mechanism of stop codon recognition and peptidyl-tRNA hydrolysis. RA Song H, Mugnier P, Das AK, Webb HM, Evans DR, Tuite MF, Hemmings BA, Barford D RL Cell. 2000 Feb 4;100(3):311-21.
Genome PropertyGenProp0831: archaeal core gene set, exactly 1 per genome (HMM)