HMM Summary Page: TIGR02562

FunctionCRISPR-associated helicase Cas3, subtype I-F/YPEST
Gene Symbolcas3f
Trusted Cutoff565.95
Domain Trusted Cutoff565.95
Noise Cutoff452.40
Domain Noise Cutoff452.40
Isology Typeequivalog
HMM Length1110
Mainrole CategoryMobile and extrachromosomal element functions
Subrole CategoryOther
Gene Ontology TermGO:0004386: helicase activity molecular_function
GO:0043571: maintenance of CRISPR repeat elements biological_process
AuthorHaft DH
Entry DateApr 25 2005 12:02PM
Last ModifiedFeb 14 2011 3:27PM
CommentThe helicase in many CRISPR-associated (cas) gene clusters is designated Cas3, and most Cas3 proteins are described by model TIGR01587. Members of this family are considerably larger, show a number of motifs in common with TIGR01587 sequences, and replace Cas3 in some CRISPR/cas loci in a number of Proteobacteria, including Yersinia pestis, Chromobacterium violaceum, Erwinia carotovora subsp. atroseptica SCRI1043, Photorhabdus luminescens subsp. laumondii TTO1, Legionella pneumophila, etc.
ReferencesDR URL DR URL RN [1] RT A guild of 45 CRISPR-associated (Cas) protein families and multiple CRISPR/cas subtypes exist in prokaryotic genomes RA Haft DH, Selengut JD, Mongodin EF, Nelsen KE RL PLOS Comput. Biol. 1(6), e60-e69, 2005
Genome PropertyGenProp0021: CRISPR region (HMM)
GenProp0310: CRISPR system, I-F/Ypest subtype (HMM)