HMM Summary Page: TIGR02438

Functioncatechol 1,2-dioxygenase
Gene SymbolcatA
Trusted Cutoff404.40
Domain Trusted Cutoff404.40
Noise Cutoff346.50
Domain Noise Cutoff346.50
Isology Typeequivalog
EC Number1.13.11.1
HMM Length281
AuthorHaft DH
Entry DateJan 25 2005 5:02PM
Last ModifiedFeb 14 2011 3:27PM
CommentMembers of this family are catechol 1,2-dioxygenases of the Actinobacteria. They are more closely related to actinobacterial chlorocatechol 1,2-dioxygenases than to proteobacterial catechol 1,2-dioxygenases, and so are built in this separate model. The member from Rhodococcus rhodochrous NCIMB 13259 (GB|AAC33003.1) is described as a homodimer with bound Fe, similarly active on catechol, 3-methylcatechol and 4-methylcatechol.
ReferencesRM 9677336 RT Purification and characterization of catechol 1,2-dioxygenase from Rhodococcus rhodochrous NCIMB 13259 and cloning and sequencing of its catA gene. RA Strachan PD, Freer AA, Fewson CA. RL Biochem J. 1998 Aug 1;333 ( Pt 3):741-7.
Genome PropertyGenProp0711: catechol ortho-cleavage upper pathway (HMM)