HMM Summary Page: TIGR02348

Functionchaperonin GroL
Gene SymbolgroL
Trusted Cutoff582.10
Domain Trusted Cutoff582.10
Noise Cutoff306.80
Domain Noise Cutoff306.80
Isology Typeequivalog
HMM Length526
Mainrole CategoryProtein fate
Subrole CategoryProtein folding and stabilization
Gene Ontology TermGO:0005515: protein binding molecular_function
GO:0006457: protein folding biological_process
GO:0016887: ATPase activity molecular_function
AuthorHaft DH
Entry DateOct 6 2004 5:31PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis family consists of GroEL, the larger subunit of the GroEL/GroES cytosolic chaperonin. It is found in bacteria, organelles derived from bacteria, and occasionally in the Archaea. The bacterial GroEL/GroES group I chaperonin is replaced a group II chaperonin, usually called the thermosome in the Archaeota and CCT (chaperone-containing TCP) in the Eukaryota. GroEL, thermosome subunits, and CCT subunits all fall under the scope of Pfam model PF00118.
References DR HAMAP; MF_00600; 808 of 844
Genome PropertyGenProp0245: chaperone system: GroEL/GroES (HMM)