HMM Summary Page: TIGR01447

Functionexodeoxyribonuclease V, alpha subunit
Gene SymbolrecD
Trusted Cutoff310.15
Domain Trusted Cutoff310.15
Noise Cutoff268.80
Domain Noise Cutoff268.80
Isology Typeequivalog
EC Number3.1.11.5
HMM Length597
Mainrole CategoryDNA metabolism
Subrole CategoryDNA replication, recombination, and repair
Gene Ontology TermGO:0006281: DNA repair biological_process
GO:0006310: DNA recombination biological_process
GO:0008854: exodeoxyribonuclease V activity molecular_function
GO:0009338: exodeoxyribonuclease V complex cellular_component
AuthorHaft DH
Entry DateFeb 21 2002 12:44PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis family describes the exodeoxyribonuclease V alpha subunit, RecD. RecD is part of a RecBCD complex. A related family in the Gram-positive bacteria separates in a phylogenetic tree, has an additional N-terminal extension of about 200 residues, and is not supported as a member of a RecBCD complex by neighboring genes. The related family is consequently described by a different model.
ReferencesDR EXPERIMENTAL; GP|3063663; Neisseria gonorrhoeae DR EXPERIMENTAL; SP|P04993; Escherichia coli
Genome PropertyGenProp0216: recBCD pathway (HMM)