HMM Summary Page: TIGR01193

FunctionABC-type bacteriocin transporter
Trusted Cutoff523.85
Domain Trusted Cutoff523.85
Noise Cutoff460.50
Domain Noise Cutoff460.50
Isology Typesubfamily
HMM Length708
Mainrole CategoryProtein fate
Subrole CategoryProtein and peptide secretion and trafficking
Gene Ontology TermGO:0043190: ATP-binding cassette (ABC) transporter complex cellular_component
GO:0043213: bacteriocin transport biological_process
GO:0043214: bacteriocin-transporting ATPase activity molecular_function
AuthorHaft DH, Ujwal ML, Paulsen IT
Entry DateMar 4 2001 11:07PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis model describes ABC-type bacteriocin transporter. The amino terminal domain (PF03412) processes the N-terminal leader peptide from the bacteriocin while C-terminal domains resemble ABC transporter membrane protein and ATP-binding cassette domain. In general, bacteriocins are agents which are responsible for killing or inhibiting the closely related species or even different strains of the same species. Bacteriocins are usually encoded by bacterial plasmids. Bacteriocins are named after the species and hence in literature one encounters various names e.g., leucocin from Leuconostic geldium; pedicocin from Pedicoccus acidilactici; sakacin from Lactobacillus sake etc.
ReferencesRM 10085080 RT Membrane topology of the lactococcal bacteriocin ATP-binding cassette transporter protein LcnC. Involvement of LcnC in lactococcin a maturation. RA Franke CM, Tiemersma J, Venema G, Kok J. RL J Biol Chem 1999 Mar 26;274(13):8484-90
Genome PropertyGenProp0808: bacteriocin system, TIGR01847 leader group (HMM)