| Accession | TIGR01051 |
| Name | topA_bact |
| Function | DNA topoisomerase I |
| Gene Symbol | topA |
| Trusted Cutoff | 456.40 |
| Domain Trusted Cutoff | 456.40 |
| Noise Cutoff | 379.15 |
| Domain Noise Cutoff | 379.15 |
| Isology Type | equivalog |
| EC Number | 5.99.1.2 |
| HMM Length | 632 |
| Mainrole Category | DNA metabolism |
| Subrole Category | DNA replication, recombination, and repair |
| Gene Ontology Term | GO:0003677: DNA binding molecular_function |
| | GO:0003917: DNA topoisomerase type I activity molecular_function |
| | GO:0005737: cytoplasm cellular_component |
| | GO:0006260: DNA replication biological_process |
| | GO:0006265: DNA topological change biological_process |
| Author | Ujwal ML, Haft DH |
| Entry Date | Nov 27 2000 1:17PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | This model describes DNA topoisomerase I among the members of bacteria. DNA topoisomerase I transiently cleaves one DNA strand and thus relaxes negatively supercoiled DNA during replication, transcription and recombination events. |
