HMM Summary Page: TIGR01051

FunctionDNA topoisomerase I
Gene SymboltopA
Trusted Cutoff456.40
Domain Trusted Cutoff456.40
Noise Cutoff379.15
Domain Noise Cutoff379.15
Isology Typeequivalog
EC Number5.99.1.2
HMM Length632
Mainrole CategoryDNA metabolism
Subrole CategoryDNA replication, recombination, and repair
Gene Ontology TermGO:0003677: DNA binding molecular_function
GO:0003917: DNA topoisomerase type I activity molecular_function
GO:0005737: cytoplasm cellular_component
GO:0006260: DNA replication biological_process
GO:0006265: DNA topological change biological_process
AuthorUjwal ML, Haft DH
Entry DateNov 27 2000 1:17PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis model describes DNA topoisomerase I among the members of bacteria. DNA topoisomerase I transiently cleaves one DNA strand and thus relaxes negatively supercoiled DNA during replication, transcription and recombination events.