HMM Summary Page: TIGR00595

Functionprimosomal protein N'
Gene SymbolpriA
Trusted Cutoff230.35
Domain Trusted Cutoff230.35
Noise Cutoff95.85
Domain Noise Cutoff95.85
Isology Typeequivalog
EC Number3.6.1.-
HMM Length509
Mainrole CategoryDNA metabolism
Subrole CategoryDNA replication, recombination, and repair
Gene Ontology TermGO:0003688: DNA replication origin binding molecular_function
GO:0004003: ATP-dependent DNA helicase activity molecular_function
GO:0005658: alpha DNA polymerase:primase complex cellular_component
GO:0006260: DNA replication biological_process
GO:0016818: hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides molecular_function
AuthorLoftus BJ, Eisen JA
Entry DateOct 19 1999 6:19PM
Last ModifiedFeb 14 2011 3:27PM
CommentAll proteins in this family for which functions are known are components of the primosome which is involved in replication, repair, and recombination.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
ReferencesA2 hmmalign GA hmmsearch GA hmmsearch DR EGAD; 19358; RM 90280426; DR SWISSPROT; P17888;
Genome PropertyGenProp1081: replication restart, PriA/PriB primosome pathway (HMM)