HMM Summary Page: TIGR00332

Functiondesulfoferrodoxin ferrous iron-binding domain
Trusted Cutoff61.90
Domain Trusted Cutoff61.90
Noise Cutoff36.75
Domain Noise Cutoff36.75
Isology Typedomain
HMM Length107
Mainrole CategoryEnergy metabolism
Subrole CategoryElectron transport
AuthorHaft DH
Entry DateApr 20 1999 2:08PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis domain comprises essentially the full length of neelaredoxin, a monomeric, blue, non-heme iron protein of Desulfovibrio gigas said to bind two iron atoms per monomer with identical spectral properties. Neelaredoxin was shown recently to have significant superoxide dismutase activity. This domain is also found (in a form in which the distance between the motifs H[HWYF]IXW and CN[IL]HGXW is somewhat shorter) as the C-terminal domain of desulfoferrodoxin, which is said to bind a single ferrous iron atom. The N-terminal domain of desulfoferrodoxin is described in a separate HMM, dfx_rbo (TIGR00320).
ReferencesA2 hmmalign RN [1] RM 95094820 RT A blue non-heme iron protein from Desulfovibrio gigas. RA Chen L, Sharma P, Le Gall J, Mariano AM, Teixeira M, Xavier AV RL Eur J Biochem 1994 Dec 1;226(2):613-8 RN [2] RM 99115446 RT Desulfovibrio gigas neelaredoxin. A novel superoxide dismutase integrated in a putative oxygen sensory operon of an anaerobe. RA Silva G, Oliveira S, Gomes CM, Pacheco I, Liu MY, Xavier AV, Teixeira M, Legall J, Rodrigues-pousada C RL Eur J Biochem 1999 Jan;259(1-2):235-43 SE TIGR GA hmmls AL clustalw BD 0414