HMM Summary Page: TIGR00066

Gene Symbolggt
Trusted Cutoff357.85
Domain Trusted Cutoff357.85
Noise Cutoff182.70
Domain Noise Cutoff182.70
Isology Typeequivalog
EC Number2.3.2.2
HMM Length518
Mainrole CategoryBiosynthesis of cofactors, prosthetic groups, and carriers
Subrole CategoryGlutathione and analogs
Gene Ontology TermGO:0003840: gamma-glutamyltransferase activity molecular_function
GO:0006750: glutathione biosynthetic process biological_process
AuthorHaft DH
Entry DateApr 20 1999 2:07PM
Last ModifiedFeb 14 2011 3:27PM
CommentAlso called gamma-glutamyltranspeptidase (ggt). Some members of this family have antibiotic synthesis or resistance activities. In the case of a cephalosporin acylase from Pseudomonas sp., the enzyme was shown to retain some gamma-glutamyltranspeptidase activity. Other, more distantly related proteins have ggt-related activities and score below the trusted cutoff.
ReferencesA2 hmmalign SE TIGR GA hmmls AL clustalw, seaview BD build_dir/0135