HMM Summary Page: TIGR04566

Functionouter membrane exchange protein TraA, N-terminal region
Gene SymboltraA
Trusted Cutoff80.00
Domain Trusted Cutoff80.00
Noise Cutoff35.00
Domain Noise Cutoff35.00
Isology Typesubfamily_domain
HMM Length240
AuthorHaft DH
Entry DateSep 11 2014 1:29PM
Last ModifiedSep 11 2014 1:36PM
CommentIn Myxococcus xanthus, the protein pair TraA (MXAN_6895) and TraB (MXAN_6898) are required for contact-dependent exchange of outer membrane proteins. The C-terminal half of TrA consists largely of Cys-rich tandem repeats. This model describes the N-terminal region of TraA, and related protein MXAN_4924. This region is suggested to be similar to the lectin PA14. Members of this family are restricted to a subset of the Myxococcales, and so have a narrower species distribution than the MYXO-CTERM putative protein sorting signal (TIGR03901), which is universal in the Myxococcales. Note that TIGR04201 matches at least seven repeats in the C-terminal region of TraA. T
ReferencesRN [1] RM PMID:22511878 RT Cell contact-dependent outer membrane exchange in myxobacteria: genetic determinants and mechanism. RA Pathak DT, Wei X, Bucuvalas A, Haft DH, Gerloff DL, Wall D RL PLoS Genet. 2012;8(4):e1002626. doi: 10.1371/journal.pgen.1002626.