HMM Summary Page: TIGR04544

Functionbeta-methylarginine biosynthesis bifunctional aminotransferase
Trusted Cutoff350.00
Domain Trusted Cutoff350.00
Noise Cutoff180.00
Domain Noise Cutoff180.00
Isology Typeequivalog
EC Number2.6.-.-
HMM Length366
AuthorHaft DH
Entry DateJun 24 2014 3:06PM
Last ModifiedSep 16 2014 4:02PM
CommentMembers of this family are the bifunctional aminotransferase that catalyzes the first and third steps in the three-step conversion of arginine to beta-methylarginine. It first converts arginine to 2-ketoarginine, then converts 3-methyl-2-ketoarginine to 3-methylarginine. All members of the seed alignment are encoded next to a 2-ketoarginine methyltransferase (EC
ReferencesRN [1] RM PMID:20190091 RT Identification of the biosynthetic gene cluster for 3-methylarginine, a toxin produced by Pseudomonas syringae pv. syringae 22d/93. RA Braun SD, Hofmann J, Wensing A, Ullrich MS, Weingart H, Volksch B, Spiteller D RL Appl Environ Microbiol. 2010 Apr;76(8):2500-8. doi: 10.1128/AEM.00666-09. RN [2] RM PMID:24907335 RT Biosynthesis of beta-Methylarginine residue of Peptidyl Nucleoside Arginomycin in Streptomyces arginensis NRRL 15941. RA Feng J, Wu J, Gao J, Xia Z, Deng Z, He X RL Appl Environ Microbiol. 2014 Jun 6. pii: AEM.01172-14.
Genome PropertyGenProp1098: 3-methylarginine biosynthesis (HMM)