HMM Summary Page: TIGR04528

Functionacido-empty-quinoprotein group A
Trusted Cutoff650.00
Domain Trusted Cutoff650.00
Noise Cutoff575.00
Domain Noise Cutoff575.00
Isology Typesubfamily
HMM Length493
AuthorHaft DH
Entry DateApr 17 2014 7:47PM
Last ModifiedSep 16 2014 4:02PM
CommentMembers of this family closely resemble quinoproteins and quinohemoproteins such as PQQ-dependent methanol, glucose, and shikimate dehydrogenases, but restricted to species of Acidobacteria unable to synthesize PQQ. Seven members occur in candidatus Solibacter usitatus Ellin6076, eleven in Acidobacteriaceae bacterium KBS 96, etc. Members have N-terminal signal sequences. They lack the pair of adjacent Cys residues, involved in electron transfer, typical for family TIGR03075, and they lack CxxCH motifs for cytochrome c-like heme-binding. What cofactor these paralogous families of enzymes might use is unclear.