HMM Summary Page: TIGR04526

Functionputative immunoglobulin-blocking virulence protein
Trusted Cutoff150.00
Domain Trusted Cutoff150.00
Noise Cutoff45.00
Domain Noise Cutoff45.00
Isology Typesubfamily
HMM Length693
AuthorHaft DH
Entry DateApr 7 2014 12:14PM
Last ModifiedSep 16 2014 4:02PM
CommentMembers of this family are putative virulence proteins of Mycoplasma and Ureaplasma species. Members share a region of sequence similarity (see TIGR04524) with protein M, a Mycoplasma genitalium protein that binds a conserved light chain region of IgG and blocks its protective function of antigen-specific binding. The seed alignment for this model includes an N-terminal signal-anchor domain and a proline-rich linker domain, and a C-terminal extension, in addition to the protein M-like domain recognized by TIGR04524.