HMM Summary Page: TIGR04519

FunctionMoCo/4Fe-4S cofactor protein extended Tat translocation domain
Trusted Cutoff20.60
Domain Trusted Cutoff20.60
Noise Cutoff20.50
Domain Noise Cutoff19.50
Isology Typeequivalog_domain
HMM Length45
AuthorHaft DH
Entry DateMar 19 2014 2:08PM
Last ModifiedSep 16 2014 4:02PM
CommentThis model describes a forty-five residue domain in which the last six residues represent the start of a TAT (Twin-Arginine Translocation) sorting signal. TAT allows proteins already folded, with cofactor already bound, to transit the membrane and reach the periplasm with the ability to perform redox or other cofactor-dependent activities. TAT signals are not normally seen so far from a well-supported start site. Member proteins may all be mutually homologous, with both a molybdenum cofactor-binding domain and a 4Fe-4S dicluster-binding domain.