HMM Summary Page: TIGR04516

Functionglycosyltransferase, activator-dependent family
Trusted Cutoff440.00
Domain Trusted Cutoff440.00
Noise Cutoff400.00
Domain Noise Cutoff400.00
Isology Typesubfamily
EC Number2.4.1.-
HMM Length418
AuthorHaft DH
Entry DateMar 4 2014 4:38PM
Last ModifiedSep 16 2014 4:02PM
CommentMany biosynthesis clusters for secondary metabolites feature a glycosyltransferase gene next to a P450 homolog, often with the P450 lacking a critical heme-binding Cys. These P540-derived sequences seem to be allosteric activators of glycosyltransferases such as the member of this family. This HMM describes a set of related glycosyltransferases, many of which can be recognized as activator-dependent from genomic context.