HMM Summary Page: TIGR04508

Function7-carboxy-7-deazaguanine synthase
Gene SymbolqueE
Trusted Cutoff240.00
Domain Trusted Cutoff240.00
Noise Cutoff200.00
Domain Noise Cutoff200.00
Isology Typeequivalog
EC Number4.3.99.3
HMM Length208
AuthorHaft DH
Entry DateJan 22 2014 12:08PM
Last ModifiedJan 22 2014 12:08PM
CommentIn the pathway of 7-cyano-7-deazaquanine (preQ0) biosynthesis, the radical SAM enzyme QueE is quite variable. This HMM describes a variant form in which the three-Cys motif that binds the signature 4Fe-4S cluster takes the form Cx14CxxC, as in Burkholderia multivorans ATCC 17616. The crystal structure is known.