HMM Summary Page: TIGR04504

FunctionSDR family mycofactocin-dependent oxidoreductase
Trusted Cutoff250.00
Domain Trusted Cutoff250.00
Noise Cutoff235.00
Domain Noise Cutoff235.00
Isology Typesubfamily
EC Number1.1.99.-
HMM Length260
AuthorHaft DH
Entry DateDec 16 2013 3:30PM
Last ModifiedDec 16 2013 3:30PM
CommentMembers of this protein subfamily are putative oxidoreductases belonging to the larger SDR family. All members occur in genomes that encode a cassette for the biosynthesis of mycofactocin, a proposed electron carrier of a novel redox pool. Characterized members of this family are described as NDMA-dependent, meaning that a blue aniline dye serving as an artificial electron acceptor is required for members of this family to cycle in vitro, since the bound NAD residue is not exchangeable. This family resembles TIGR03971 most closely in the N-terminal region, consistent with the published hypothesis of NAD interaction with mycofactocin. See EC
Genome PropertyGenProp0917: mycofactocin system (HMM)