| Accession | TIGR04498 |
| Name | AbiV_defense |
| Function | abortive infection protein, AbiV family |
| Trusted Cutoff | 27.00 |
| Domain Trusted Cutoff | 26.00 |
| Noise Cutoff | 23.00 |
| Domain Noise Cutoff | 23.00 |
| Isology Type | subfamily |
| HMM Length | 143 |
| Author | Haft DH |
| Entry Date | Dec 5 2013 1:55PM |
| Last Modified | Dec 5 2013 1:55PM |
| Comment | This family includes AbiV (abortive infection system V) from Lactococcus lactis, a phage resistance protein that causes certain phage infections to fail to lead to successful phage replication. Abortive infection mechanisms differ greatly. AbiV interacts directly with the protein SaV in phage p2 and blocks translation of phage proteins. |
| References | RN [1]
RM PMID:20851990
RT Lactococcal abortive infection protein AbiV interacts directly with the phage protein SaV and prevents translation of phage proteins.
RA Haaber J, Samson JE, Labrie SJ, Campanacci V, Cambillau C, Moineau S, Hammer K
RL Appl Environ Microbiol. 2010 Nov;76(21):7085-92. doi: 10.1128/AEM.00093-10. |
| Genome Property | GenProp1093: abortive infection proteins (HMM) |
