HMM Summary Page: TIGR04483

FunctionD-proline reductase (dithiol), PrdB protein
Gene SymbolprdB
Trusted Cutoff300.00
Domain Trusted Cutoff300.00
Noise Cutoff225.00
Domain Noise Cutoff225.00
Isology Typeequivalog
EC Number1.21.4.1
HMM Length238
AuthorHaft DH
Entry DateSep 13 2013 4:05PM
Last ModifiedSep 13 2013 4:05PM
CommentMembers of this family form the PrdB subunit, usually a selenoprotein, in the D-proline reductase complex. The usual pathway is conversion of L-protein to D-proline by a racemase, then use of D-proline as an electron acceptor coupled to ATP generation under anaerobic conditions.
ReferencesRN [1] RM PMID:23222730 RT Proline-dependent regulation of Clostridium difficile Stickland metabolism. RA Bouillaut L, Self WT, Sonenshein AL RL J Bacteriol. 2013 Feb;195(4):844-54. doi: 10.1128/JB.01492-12.