HMM Summary Page: TIGR04482

Functionproline reductase cluster protein PrdD
Gene SymbolprdD
Trusted Cutoff320.00
Domain Trusted Cutoff320.00
Noise Cutoff310.00
Domain Noise Cutoff310.00
Isology Typeequivalog
HMM Length246
AuthorHaft DH
Entry DateSep 13 2013 2:51PM
Last ModifiedSep 13 2013 2:51PM
CommentMembers of this family are PrdD, encoded in the proline reductase gene cluster. Members are closely homologous to PrdA, which cleaves during maturation to create two subunits of the subunits of the proline reductase complex, one of which has a Cys-derived pyruvoyl active site.
ReferencesRN [1] RM PMID:23222730 RT Proline-dependent regulation of Clostridium difficile Stickland metabolism. RA Bouillaut L, Self WT, Sonenshein AL RL J Bacteriol. 2013 Feb;195(4):844-54. doi: 10.1128/JB.01492-12.