Accession | TIGR04477 |
Name | sorted_by_XrtN |
Function | XrtN system VIT domain protein |
Trusted Cutoff | 250.00 |
Domain Trusted Cutoff | 250.00 |
Noise Cutoff | 125.00 |
Domain Noise Cutoff | 125.00 |
Isology Type | hypoth_equivalog |
HMM Length | 822 |
Author | Haft DH |
Entry Date | Aug 30 2013 2:51PM |
Last Modified | Aug 30 2013 2:51PM |
Comment | Members of this subfamily average about 850 amino acids in length, ending with a variant form of PEP-CTERM sorting signal. Members have a VIT (vault protein inter-alpha-trypsin inhibitor heavy chain) domain (PF08487). Other bacterial subfamilies of VIT domain proteins have members with either GlyGly-CTERM or LPXTG C-terminal sorting signals. Members of this subfamily occur only in context next to a protein sorting/processing enzyme, exosortase N (XrtN). These subsystems occur both among the Bacteriodetes and in the spirochete genus Leptospira. |
References | RN [1]
RM PMID:22037399
RT Archaeosortases and exosortases are widely distributed systems linking membrane transit with posttranslational modification.
RA Haft DH, Payne SH, Selengut JD
RL J Bacteriol. 2012 Jan;194(1):36-48. doi: 10.1128/JB.06026-11. |
Genome Property | GenProp1087: protein sorting system, vault protein/exosortase N (HMM) |