HMM Summary Page: TIGR04474

Functionthree-Cys-motif partner protein
Gene SymboltcmP
Trusted Cutoff53.00
Domain Trusted Cutoff53.00
Noise Cutoff40.00
Domain Noise Cutoff40.00
Isology Typesubfamily
HMM Length263
AuthorHaft DH
Entry DateAug 28 2013 3:41PM
Last ModifiedAug 28 2013 3:41PM
CommentMembers of this family occur regularly as a partner to as a member of family PF07505, which has been called a phage protein but which seems to occur also in other contexts. Members average about 400 residues in length, but the conserved region covered by the model averages 260 residues and excludes the C-terminus. Conserved motifs suggest enzymatic activity. Note that its frequent partner protein (see PF07505) has a three-cysteine motif that resembles the Cx3CxxC motif of radical SAM proteins, and that in one branch (see TIGR04471) actually becomes Cx3CxxC. We suggest the name three-Cys-motif partner protein (tcmP), and renaming PF07505 to three-Cys-motif family protein
Genome PropertyGenProp1100: mobile element associated three-Cys-motif pair (HMM)