HMM Summary Page: TIGR04471

Functionradical SAM mobile pair protein A
Trusted Cutoff355.00
Domain Trusted Cutoff355.00
Noise Cutoff280.00
Domain Noise Cutoff280.00
Isology Typehypoth_equivalog
HMM Length220
AuthorHaft DH
Entry DateAug 25 2013 7:51PM
Last ModifiedAug 25 2013 7:51PM
CommentMembers of this family are the upstream member (A) of a pair of tandem-encoded radical SAM enzymes. Most of these radical SAM gene pairs have an additional upstream regulatory gene in the MarR family. Examples of high sequence identity (over 96 percent) from cassettes in several Treponema species of the oral cavity to those in multiple Firmicutes in the gut microbiome suggest recent lateral gene transfer, as might be expected for antibiotic resistance genes. The function is unknown.
Genome PropertyGenProp1086: Firmicutes/Treponema mobile radical SAM system (HMM)