HMM Summary Page: TIGR04470

Functionradical SAM mobile pair protein B
Trusted Cutoff410.00
Domain Trusted Cutoff410.00
Noise Cutoff375.00
Domain Noise Cutoff375.00
Isology Typehypoth_equivalog
HMM Length285
AuthorHaft DH
Entry DateAug 25 2013 7:26PM
Last ModifiedAug 25 2013 7:26PM
CommentMembers of this family are the downstream member (B) of a pair of tandem-encoded radical SAM enzymes. Most of these radical SAM gene pairs have an additional upstream regulatory gene in the MarR family. Examples of high sequence identity (over 96 percent) from cassettes in several Treponema species of the oral cavity to those in multiple Firmicutes in the gut microbiome suggest recent lateral gene transfer, as might be expected for antibiotic resistance genes. The function is unknown.
Genome PropertyGenProp1086: Firmicutes/Treponema mobile radical SAM system (HMM)