| Comment | Members of this family are arginine 2,3-aminomutase, a radical SAM enzyme more closely related to lysine 2,3-aminomutase than to glutamate 2,3-aminomutase. The enzyme makes L-beta-arginine, sometimes in the context of antibiotic biosynthesis (blasticidin S, mildiomycin, etc). Activity is proven in Streptomyces griseochromogenes, which makes blasticidin S. |
| References | RN [1]
RT Biosynthesis of blasticidin S from L-alpha-arginine. Stereochemistry in the arginine-2,3-aminomutase reaction.
RA Prabhakaran PC, Woo NT, Yorgey PS, Gould SJ
RL J. Am. Chem. Soc., 1988, 110 (17), 5785–5791 |
