HMM Summary Page: TIGR04450

Functionputative immunity protein/bacteriocin
Trusted Cutoff27.00
Domain Trusted Cutoff27.00
Noise Cutoff25.00
Domain Noise Cutoff25.00
Isology Typesubfamily
HMM Length240
AuthorHaft DH
Entry DateJun 14 2013 3:36PM
Last ModifiedJun 14 2013 3:36PM
CommentThis model describes full-length proteins of Gram-positive bacteria that consist of an N-terminal signal peptide, a central region of unknown function, and a Cys-rich C-terminal region. In both the overall architecture and the apparent weak homology of the C-terminal region itself, these proteins resemble archaeal proteins such as the halocin C8 precursor. In that precursor, the C-terminal region is a bacteriocin but the N-terminal region functions as the immunity protein. The related family of halocin C8-like bacteriocins and their bacterial homologs are recognized by model TIGR04449.