| Accession | TIGR04446 |
| Name | pren_cyc_PirE |
| Function | prenylated cyclic peptide, anacyclamide/piricyclamide family |
| Trusted Cutoff | 35.00 |
| Domain Trusted Cutoff | 35.00 |
| Noise Cutoff | 31.00 |
| Domain Noise Cutoff | 31.00 |
| Isology Type | subfamily |
| HMM Length | 51 |
| Author | Haft DH |
| Entry Date | Jun 5 2013 8:36PM |
| Last Modified | Jun 5 2013 8:36PM |
| Comment | Members of this protein family occur primarily in Cyanobacteria. They average about 50 residues in length and are the ribosomally translated precursors of peptide natural products whose modifications include cleavage, cyclization, and prenylation. Sequences are well-conserved in the N-terminal region. They are nearly invariant over the last eight residues, but hypervariable just before that stretch. A related family, often in a similar genome context, is TIGR03678. |
| References | RN [1]
RM PMID:21766822
RT Enzymatic basis of ribosomal peptide prenylation in cyanobacteria.
RA McIntosh JA, Donia MS, Nair SK, Schmidt EW
RL J Am Chem Soc. 2011 Aug 31;133(34):13698-705. |
| Genome Property | GenProp1083: cyanobactin-like ribosomal natural product biosynthesis (HMM) |
