| Accession | TIGR04443 |
| Name | F420_CofF |
| Function | coenzyme gamma-F420-2:alpha-L-glutamate ligase |
| Gene Symbol | cofF |
| Trusted Cutoff | 300.00 |
| Domain Trusted Cutoff | 300.00 |
| Noise Cutoff | 150.00 |
| Domain Noise Cutoff | 150.00 |
| Isology Type | equivalog |
| EC Number | 6.3.2.32 |
| HMM Length | 283 |
| Author | Haft DH |
| Entry Date | May 24 2013 3:22PM |
| Last Modified | May 24 2013 3:22PM |
| Comment | Members of this family are the CofF, a RimK-related glutamate ligase that caps the gamma-glutamyl tail of the archaeal form of coenzyme F420, a hydride carrier. This enzyme does not appear in bacterial species, such as Mycobacterium tuberculosis, that make F420 with a different type of tail. |
| References | RN [1]
RM PMID:12909715
RT Glutathione synthetase homologs encode alpha-L-glutamate ligases for methanogenic coenzyme F420 and tetrahydrosarcinapterin biosyntheses.
RA Li H, Xu H, Graham DE, White RH
RL Proc Natl Acad Sci U S A. 2003 Aug 19;100(17):9785-90. |
| Genome Property | GenProp0791: coenzyme F420 biosynthesis (HMM) |
