HMM Summary Page: TIGR04439

Functionputative histamine N-monooxygenase
Gene SymbolbasC
Trusted Cutoff700.00
Domain Trusted Cutoff700.00
Noise Cutoff550.00
Domain Noise Cutoff550.00
Isology Typeequivalog
EC Number1.14.13.-
HMM Length431
AuthorHaft DH
Entry DateMay 8 2013 5:49PM
Last ModifiedMay 8 2013 5:49PM
CommentMembers of this family are involved in synthesizing N-hydroxyhistamine as a precursor to acinetobactin, a siderophore found in Acinetobacter baumannii. Assuming histidine is first decarboxylated to histamine, then hydroxylated, members of this family are histamine N-monooxygenase. The putative histidine decarboxylase is found in the same biosynthetic cluster.
ReferencesRN [1] RM PMID:15289555 RT Identification and transcriptional organization of a gene cluster involved in biosynthesis and transport of acinetobactin, a siderophore produced by Acinetobacter baumannii ATCC 19606T. RA Mihara K, Tanabe T, Yamakawa Y, Funahashi T, Nakao H, Narimatsu S, Yamamoto S RL Microbiology. 2004 Aug;150(Pt 8):2587-97.