HMM Summary Page: TIGR04437

Function3-deoxy-D-manno-oct-2-ulosonate III transferase WaaZ
Gene SymbolwaaZ
Trusted Cutoff200.00
Domain Trusted Cutoff200.00
Noise Cutoff40.00
Domain Noise Cutoff40.00
Isology Typeequivalog
EC Number2.4.1.-
HMM Length252
AuthorHaft DH
Entry DateMay 3 2013 5:21PM
Last ModifiedMay 3 2013 5:21PM
CommentMembers of this family are WaaZ, or Kdo-III transferase. This enzyme, present in some strains of E. coli and its allies but not others, performs a non-stoichiometric addition of a third 3-deoxy-D-manno-oct-2-ulosonic acid (KDO-III) onto some fraction of KDO-II in the lipopolysaccharide (LPS) inner core.
ReferencesRN [1] RM PMID:22021036 RT Molecular basis of lipopolysaccharide heterogeneity in Escherichia coli: envelope stress-responsive regulators control the incorporation of glycoforms with a third 3-deoxy-alpha-D-manno-oct-2-ulosonic acid and rhamnose. RA Klein G, Lindner B, Brade H, Raina S RL J Biol Chem. 2011 Dec 16;286(50):42787-807.
Genome PropertyGenProp0203: LPS inner core biosynthesis, ketodeoxyoctonate and heptose type (HMM)