HMM Summary Page: TIGR04424

FunctionMcbB family protein
Trusted Cutoff65.00
Domain Trusted Cutoff65.00
Noise Cutoff25.00
Domain Noise Cutoff25.00
Isology Typesubfamily
HMM Length286
AuthorHaft DH
Entry DateMar 14 2013 12:02PM
Last ModifiedMar 14 2013 12:02PM
CommentThis family includes the partially characterized zinc metalloprotein McbB, part of the maturase system for microcin B17, a thiazole/oxazole-modified microcin (TOMM). Other members of this family belong to very different gene neighborhoods. The Cys residues that act as zinc ligands are conserved in most members, but for rare members are jointly absent.
ReferencesRN [1] RM PMID:11123948 RT The McbB component of microcin B17 synthetase is a zinc metalloprotein. RA Zamble DB, McClure CP, Penner-Hahn JE, Walsh CT RL Biochemistry. 2000 Dec 26;39(51):16190-9.