HMM Summary Page: TIGR04418

Functionprimosomal replication protein PriB
Gene SymbolpriB
Trusted Cutoff72.00
Domain Trusted Cutoff72.00
Noise Cutoff70.00
Domain Noise Cutoff70.00
Isology Typeexception
HMM Length96
AuthorHaft DH
Entry DateFeb 26 2013 12:43PM
Last ModifiedFeb 26 2013 12:43PM
CommentMembers of this protein family are primosomal replication protein N (PriB), virtually always encoded between rpsF (ribosomal protein S6) and rpsR (ribosomal protein S18). Note that only this short form, as found primarily in the gamma-Proteobacteria, of the single-stranded DNA binding protein family (see model TIGR00621) may partner with PriA and be involved in priming for re-initiation of replication.
ReferencesRN [1] RM PMID:22938024 RT Crystal structure and DNA-binding mode of Klebsiella pneumoniae primosomal PriB protein. RA Huang YH, Lo YH, Huang W, Huang CY RL Genes Cells. 2012 Oct;17(10):837-49. RN [2] RM PMID:17588514 RT A hand-off mechanism for primosome assembly in replication restart. RA Lopper M, Boonsombat R, Sandler SJ, Keck JL RL Mol Cell. 2007 Jun 22;26(6):781-93.
Genome PropertyGenProp1081: replication restart, PriA/PriB primosome pathway (HMM)