HMM Summary Page: TIGR04416

Functiongroup II intron reverse transcriptase/maturase
Gene SymbolltrA
Trusted Cutoff300.00
Domain Trusted Cutoff300.00
Noise Cutoff180.00
Domain Noise Cutoff180.00
Isology Typeequivalog
EC Number2.7.7.49
HMM Length353
AuthorHaft DH
Entry DateFeb 13 2013 8:47AM
Last ModifiedFeb 13 2013 8:47AM
CommentMembers of this protein family are multifunctional proteins encoded in most examples of bacterial group II introns. These group II introns are mobile selfish genetic elements, often with multiple highly identical copies per genome. Member proteins have an N-terminal reverse transcriptase (RNA-directed DNA polymerase) domain (PF00078) followed by an RNA-binding maturase domain (PF08388). Some members of this family may have an additional C-terminal DNA endonuclease domain that this model does not cover. A region of the group II intron ribozyme structure should be detectable nearby on the genome by Rfam model RF00029.