HMM Summary Page: TIGR04399

Functionaccessory Sec system S-layer assembly protein
Trusted Cutoff250.00
Domain Trusted Cutoff250.00
Noise Cutoff200.00
Domain Noise Cutoff200.00
Isology Typeequivalog
HMM Length288
AuthorHaft DH
Entry DateJan 20 2013 8:02PM
Last ModifiedJan 20 2013 8:02PM
CommentMembers of this family, designated S-layer assembly protein (SlaP), occur next to a Bacillus anthracis-type accessory Sec system SecA2. . Members have two tandem copies of a duplicated domain (TIGR04398) that may also occur in other contexts. SlaP is found both free in the cytoplasm and membrane-associated. SecA2 and SlaP appear to work together to modify Sec for efficient S-layer secretion.
ReferencesRN [1] RM PMID:22609926 RT Secretion genes as determinants of Bacillus anthracis chain length. RA Nguyen-Mau SM, Oh SY, Kern VJ, Missiakas DM, Schneewind O RL J Bacteriol. 2012 Aug;194(15):3841-50. doi: 10.1128/JB.00384-12.