HMM Summary Page: TIGR04395

Functioncholine TMA-lyase-activating enzyme
Gene SymbolcutD
Trusted Cutoff360.00
Domain Trusted Cutoff360.00
Noise Cutoff345.00
Domain Noise Cutoff345.00
Isology Typeequivalog
EC Number1.97.-.-
HMM Length309
AuthorHaft DH
Entry DateDec 21 2012 12:42PM
Last ModifiedDec 21 2012 12:42PM
CommentMembers of this family are CutD, a radical enzyme that serves as an activase for choline TMA-lyase, CutC. CutC is a glycyl radical enzyme related to pyruvate formate-lyase, and this enzyme, CutD, is related to pyruvate formate-lyase activase.
ReferencesRN [1] RM PMID:23151509 RT Microbial conversion of choline to trimethylamine requires a glycyl radical enzyme. RA Craciun S, Balskus EP RL Proc Natl Acad Sci U S A. 2012 Nov 14.
Genome PropertyGenProp1076: choline TMA-lyase system (HMM)