HMM Summary Page: TIGR04381

FunctionTyrR family helix-turn-helix domain
Trusted Cutoff30.00
Domain Trusted Cutoff30.00
Noise Cutoff28.00
Domain Noise Cutoff28.00
Isology Typedomain
HMM Length49
AuthorHaft DH
Entry DateSep 20 2012 1:18PM
Last ModifiedSep 20 2012 1:18PM
CommentThis model describes the C-terminal DNA-binding helix-turn-helix domain of several regulators of aromatic amino acid metabolism. Examples include TyrR in Escherichia coli and PhhR in Pseudomonas putida. Most members of this family have a sigma-54 interaction domain.
ReferencesRN [1] RM PMID:11344327 RT Solution structure of the DNA-binding domain of the TyrR protein of Haemophilus influenzae. RA Wang Y, Zhao S, Somerville RL, Jardetzky O RL Protein Sci. 2001 Mar;10(3):592-8.