HMM Summary Page: TIGR04375

Functionhercynine metabolism protein
Trusted Cutoff125.00
Domain Trusted Cutoff125.00
Noise Cutoff90.00
Domain Noise Cutoff90.00
Isology Typehypoth_equivalog
HMM Length155
AuthorHaft DH
Entry DateSep 6 2012 5:24PM
Last ModifiedSep 6 2012 5:33PM
CommentHercynine is the betaine (trimethylated amino group) form of histidine. This protein occurs in a conserved four-gene cyanobacterial cassette along with a EgtD, the methyltransferase that converts histidine to hercynine as in ergothioneine biosynthesis, an EgtB homolog that is likely to attach some thiol (e.g. gamma-glutamyl-cysteine) through its sulfur to the hercynine imidazole ring, and a small protein of unknown function (TIGR04374). Members are distantly related to phage shock protein A (PspA).