HMM Summary Page: TIGR04371
| Accession | TIGR04371 |
| Name | methyltran_NanM |
| Function | putative sugar O-methyltransferase |
| Trusted Cutoff | 44.00 |
| Domain Trusted Cutoff | 42.00 |
| Noise Cutoff | 41.00 |
| Domain Noise Cutoff | 41.00 |
| Isology Type | subfamily |
| EC Number | 2.1.1.- |
| HMM Length | 273 |
| Author | Haft DH |
| Entry Date | Aug 31 2012 4:47PM |
| Last Modified | Aug 31 2012 4:48PM |
| Comment | Members of this family appear to be SAM-dependent O-methyltransferases acting on sugars, based on iterated sequence searches and gene context. Members occur in Leptospira O-antigen regions, as well NanM from the biosynthesis cluster for nanchangmycin, which produces 4-O-methyl-L-rhodinose as an intermediate. |
| References | RN [1] RM PMID:12770825 RT A complete gene cluster from Streptomyces nanchangensis NS3226 encoding biosynthesis of the polyether ionophore nanchangmycin. RA Sun Y, Zhou X, Dong H, Tu G, Wang M, Wang B, Deng Z RL Chem Biol. 2003 May;10(5):431-41. |