HMM Summary Page: TIGR04371

Functionputative sugar O-methyltransferase
Trusted Cutoff44.00
Domain Trusted Cutoff42.00
Noise Cutoff41.00
Domain Noise Cutoff41.00
Isology Typesubfamily
EC Number2.1.1.-
HMM Length273
AuthorHaft DH
Entry DateAug 31 2012 4:47PM
Last ModifiedAug 31 2012 4:48PM
CommentMembers of this family appear to be SAM-dependent O-methyltransferases acting on sugars, based on iterated sequence searches and gene context. Members occur in Leptospira O-antigen regions, as well NanM from the biosynthesis cluster for nanchangmycin, which produces 4-O-methyl-L-rhodinose as an intermediate.
ReferencesRN [1] RM PMID:12770825 RT A complete gene cluster from Streptomyces nanchangensis NS3226 encoding biosynthesis of the polyether ionophore nanchangmycin. RA Sun Y, Zhou X, Dong H, Tu G, Wang M, Wang B, Deng Z RL Chem Biol. 2003 May;10(5):431-41.