HMM Summary Page: TIGR04370

Functionoligosaccharide repeat unit polymerase
Trusted Cutoff40.00
Domain Trusted Cutoff40.00
Noise Cutoff35.00
Domain Noise Cutoff35.00
Isology Typesubfamily
HMM Length396
AuthorHaft DH
Entry DateAug 31 2012 1:15PM
Last ModifiedAug 31 2012 1:33PM
CommentMembers of this subfamily of highly hydrophobic proteins, with few highly conserved residues, all may act to polymerize the oligosaccharide repeat units of surface polysaccharides, including O-antigen in Gram-negative bacteria such as Leptospira (assign gene symbol wzy) and capsular polysaccharide in Gram-positive bacteria such as Streptococcus. O-antigen biosynthesis enzymes produce a repeat unit, usually an oligosaccharide, which itself is polymerized. O-antigen polymerase, usually designated Wzy. This family bears homology to the O-antigen ligase WaaL, but known examples of WaaL fall outside the bounds defined here. This model is much broader than Pfam model PF14296.
Genome PropertyGenProp0968: O-antigen polymerization/export system wzx/wzy/wzz (HMM)