| Accession | TIGR04367 |
| Name | HpnR_B12_rSAM |
| Function | hopanoid C-3 methylase HpnR |
| Gene Symbol | hpnR |
| Trusted Cutoff | 650.00 |
| Domain Trusted Cutoff | 650.00 |
| Noise Cutoff | 350.00 |
| Domain Noise Cutoff | 350.00 |
| Isology Type | equivalog |
| HMM Length | 490 |
| Author | Haft DH |
| Entry Date | Aug 9 2012 1:56PM |
| Last Modified | Aug 12 2012 6:56PM |
| Comment | Members of this are family are a B12-binding domain/radical SAM domain protein required for 3-methylhopanoid production. Activity was confirmed by mutant phenotype by disrupting this gene in Methylococcus capsulatus strain Bath. This protein family should only occur in genomes that encode a squalene-hopene cyclase (see TIGR01507). |
| References | RN [1]
RM PMID:22826256
RT Discovery, taxonomic distribution, and phenotypic characterization of a gene required for 3-methylhopanoid production.
RA Welander PV, Summons RE
RL Proc Natl Acad Sci U S A. 2012 Aug 7;109(32):12905-10. Epub 2012 Jul 23. |
| Genome Property | GenProp0761: hopanoid lipid biosynthesis (HMM) |
