HMM Summary Page: TIGR04359

Functionentry exclusion lipoprotein TrbK
Gene SymboltrbK
Trusted Cutoff23.00
Domain Trusted Cutoff22.00
Noise Cutoff22.00
Domain Noise Cutoff20.00
Isology Typeequivalog
HMM Length67
AuthorHaft DH
Entry DateJul 20 2012 9:03AM
Last ModifiedJul 20 2012 9:33AM
CommentThe characterized model example of TrbK, from incompatibility group P (IncP) plasmid RP4, is an N-terminally processed lipoprotein, localized to the periplasmic face of the plasma membrane. TrbK prevents entry through conjugation by other IncP plasmids. Unrelated, uncharacterized proteins encoded in equivalent positions in other plasmid P-type conjugative transfer regions (e.g. TIGR04360) may have analogous functions.
ReferencesRN [1] RM PMID:8955288 RT TrbK, a small cytoplasmic membrane lipoprotein, functions in entry exclusion of the IncP alpha plasmid RP4. RA Haase J, Kalkum M, Lanka E RL J Bacteriol. 1996 Dec;178(23):6720-9.