HMM Summary Page: TIGR04333

FunctionCys-rich peptide, Clo7bot family
Trusted Cutoff31.00
Domain Trusted Cutoff31.00
Noise Cutoff25.00
Domain Noise Cutoff25.00
Isology Typesubfamily
HMM Length34
AuthorHaft DH
Entry DateMay 28 2012 9:18PM
Last ModifiedMay 31 2012 6:17PM
CommentMembers of this protein family range in size from 34 to 53 residues, including from four to seven Cys residues. Multiple strains of Clostridium botulinum show seven tandem members upstream of a radical SAM/SPASM domain protein likely to act as a ribosomal natural product maturase. By analogy to subtilosin A, the Cys residues are likely targets for modifications that may introduce new crosslinks. Across multiple strains of Clostridium botulinum and C. sporogenes, the adjacent radical SAM enzyme is nearly invariant.
Genome PropertyGenProp1062: radical SAM/SPASM system Clo7bot (HMM)