HMM Summary Page: TIGR04318

Functionputative ornithine decarboxylase
Trusted Cutoff950.00
Domain Trusted Cutoff950.00
Noise Cutoff860.00
Domain Noise Cutoff860.00
Isology Typehypoth_equivalog
EC Number4.1.1.-
HMM Length695
AuthorHaft DH
Entry DateApr 22 2012 5:48PM
Last ModifiedApr 30 2012 4:24PM
CommentIn at least ten species of Lactobacillus, this close homolog to known ornithine decarboxylase occurs in a three-gene neighborhood, along with an amino acid permease family transporter and pyridoxal phosphate-dependent enyzme from the cystathionine gamma-lyase family. Species include L. acidophilus, L. amylovorus, L. crispatus, L. delbrueckii, L. farciminis, L. helveticus, L. johnsonii, etc. The combination of a decarboxylase with an antiporter in a two-gene system suggests a decarboxylation/antiport proton-motive cycle for transient resistance to acidic conditions. The substrate for this decarboxylase might be ornithine but is unknown.