HMM Summary Page: TIGR04314

Functionmethanogenesis multiheme c-type cytochrome
Trusted Cutoff250.00
Domain Trusted Cutoff250.00
Noise Cutoff75.00
Domain Noise Cutoff75.00
Isology Typeequivalog
HMM Length494
AuthorHaft DH
Entry DateApr 16 2012 11:05AM
Last ModifiedApr 16 2012 2:21PM
CommentMembers of this protein family are multiheme cytochrome c proteins of Methanosarcina acetivorans C2A and several other archaeal methanogens. All members have N-terminal signal peptides and are presumed to act in electron transfer reactions associated with methanogenesis. Putative heme-binding motifs include five (or six) CXXCH motifs, a CXXXCH motif, and a CXXXXCH motif. These proteins show multiple regions of local homology, in the same order, with multiheme cytochrome c proteins such as octaheme tetrathionate reductase from Shewanella.