HMM Summary Page: TIGR04311

Functionputative metalloenzyme radical SAM/SPASM domain maturase
Trusted Cutoff400.00
Domain Trusted Cutoff400.00
Noise Cutoff300.00
Domain Noise Cutoff300.00
Isology Typesubfamily
HMM Length423
AuthorHaft DH
Entry DateApr 9 2012 5:23PM
Last ModifiedApr 10 2012 12:33PM
CommentThis HMM describes a family of radical SAM/SPASM enzymes largely from the deltaproteobacteria. The family is most closely related to radical SAM enzyme family regularly in archaea in the vicinity of tungsten-containing oxidoreductases. A single member of the family in archaea may correspond to multiple tungsten enzymes, e.g. five in Pyrococcus furiosus. Therefore, the lack of a conserved gene neighborhood for members of this family in deltaprotebacteria suggests members may be involved in the maturation of multiple metalloenzymes.