HMM Summary Page: TIGR04285

Functionnucleoid occlusion protein
Gene Symbolnoc
Trusted Cutoff315.00
Domain Trusted Cutoff315.00
Noise Cutoff290.00
Domain Noise Cutoff290.00
Isology Typeexception
HMM Length255
AuthorHaft DH
Entry DateFeb 21 2012 4:36PM
Last ModifiedFeb 21 2012 4:39PM
CommentThis model describes nucleoid occlusion protein, a close homolog to ParB chromosome partitioning proteins including Spo0J in Bacillus subtilis. Its gene often is located near the gene for the Spo0J ortholog. This protein bind a specific DNA sequence and blocks cytokinesis from happening until chromosome segregation is complete.
ReferencesRN [1] RM PMID:19494834 RT Noc protein binds to specific DNA sequences to coordinate cell division with chromosome segregation. RA Wu LJ, Ishikawa S, Kawai Y, Oshima T, Ogasawara N, Errington J RL EMBO J. 2009 Jul 8;28(13):1940-52.